Erler-Zimmer GmbH & Co. KG Astrocytoma 3D model:
- Model code: MP2014
- Clinical history
- A 73-year-old woman was admitted with new onset left hemiplegia. On further questioning, she revealed a 3-month history of headache, nausea, and worsening balance. A CT brain scan showed an inoperable brain tumor. She died 1 week after admission.
- Pathology
- This brain specimen is a coronal section. There is an ill-defined tumor in the right sacral lobe. Hemispheric enlargement and leveling of the forestomach pattern are noted. From the posterior part of the specimen, a subfalcate herniation is seen, and the tumors appear less differentiated with hemorrhagic and necrotic foci. Histology of this tumor showed an astrocytoma, grade III/IV.
- Additional information
- Gliomas are the second most common type of central nervous system cancer after meningiomas. The term “glioma” refers to tumors that histologically resemble normal glial cells, i.e. astrocytes, oligodendrocytes, and ependymal cells. They arise from a progenitor cell that differentiates into one of the cell lineages. Astrocytomas develop from the astrocyte lineage of glial cells. The tumors are classified according to their histological differentiation and range from diffuse astrocytoma (grade II/IV) to anaplastic astrocytoma (grade III/IV) to glioblastoma (grade IV). Histological features include a prominent eosinophilic cytoplasmic content of some astrocytic tumor cells (gemistocytes) as well as a fibrillar background.
Astrocytoma 3D models – Erler-Zimmer Anatomy Group
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