Name: Daugiaformės Glioblastomos 3D Modelis Erler-Zimmer Glioblastoma Multiforme 3D Printed Model - Labostera
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„Erler-Zimmer GmbH & Co. KG Glioblastoma Multiforme 3D Model:

Model code: MP2015
Clinical history:
- Over a 3-year period, a 57-year-old woman experienced recurrent headaches and memory impairment that progressed to psychiatric disturbances, and eventually vomiting and meningeal signs. Neurological signs were localized and only slowly developed during the course of the disease.
Pathology:
- A cross-sectional view through the cerebral hemisphere shows a round, hemorrhagic, multi-colored tumor in the left temporal lobe. Less well-defined tumor tissue extends across the midline, replacing the sphenoid bone. The ventricular system is almost completely obliterated. Further cross-sectional views through the cerebral hemisphere confirm that these apparently discrete lesions are the development of a single massive tumor.
Additional information:
- Gliomas are the second most common type of central nervous system cancer after meningiomas. The term „glioma“ refers to tumors that histologically resemble normal glial (macroglial) cells, i.e. astrocytes, oligodendrocytes, and ependymal cells. They arise from a progenitor cell that differentiates into one of the cell lineages. GBMs may arise „de novo“ in the brain or develop from lower-grade astrocytomas or oligodendrogliomas. GBMs are often referred to as grade IV astrocytomas. They are distinguished histologically from anaplastic astrocytomas by the presence of necrotic tissue surrounded by anaplastic cells, as well as hyperplastic blood vessels.

Model code: MP2016
Clinical history:
- A 56-year-old man presented with generalized seizures. He remained unconscious after the seizure and later died. The patient's subsequent history revealed a 6-month history of progressive confusion, short-term memory loss, and personality changes.
Pathology:
- Post mortem coronary sections of the brain show a 4 cm necrotic and hemorrhagic tumor. The tumor has been shown to extend from the inferior frontal lobe into the lateral ventricle. The articulatory extension is visible on examination of the posterior portion of the specimen.
Additional information:
- Gliomas are the second most common type of central nervous system cancer after meningiomas. The term „glioma“ refers to tumors that histologically resemble normal glial (macroglial) cells, i.e. astrocytes, oligodendrocytes, and ependymal cells. They arise from a progenitor cell that differentiates into one of the cell lineages. Glioblastoma multiforme (GBM; also called glioblastoma) develops from the astrocyte lineage. GBM may arise de novo in the brain or develop from lower-grade astrocytomas or oligodendrogliomas. GBM is often referred to as grade IV astrocytoma. They are distinguished histologically from anaplastic astrocytomas by the presence of necrotic tissue surrounded by anaplastic cells, as well as hyperplastic blood vessels.